Born in 1921, she was first seen in March 1983. After she had been bleeding from her bladder for 4 months, a carcinoma was diagnosed. The tumor had penetrated the bladder wall. She was given 15 radiation treatments, the last in March 1983. I started her on ascorbic acid 5 g t.i.d., niacin 500 mg t.i.d., pyridoxine 200 mg od, zinc sulfate 220 mg od, selenium 300 mcg b.i.d., and magnesium oxide 410 mg b.i.d. One month after she had increased the ascorbic acid to 16 g daily. In September 1986 the tumor recurred after she had decreased her ascorbic acid intake to 1 g per day several months before. She developed pain in her left hip in December 1987 and was considered terminal. On 30 March 1988 she increased her ascorbic acid to 12 g od. She died in August 1988.

Born in 1945, she was first seen in October 1987. When I first saw her, she told me that metastases from her kidney had invaded her femur, causing a lot of pain. She received 10 radiation treatments and the pain was relieved. I started her on ascorbic acid 4 g t.i.d., niacin 500 mg t.i.d., selenium 200 mcg b.i.d., magnesium oxide 420 mg od, zinc gluconate 50 mg od, beta carotene 50,000 id od, A B complex SOs preparation od, and vitamin E 800 iu od. In November 1986 her right leg was amputated. The following April she was getting on well and was following the regimen. She was still well in September 1996.

Born in 1948, she was first seen in August 1991. In June 1991 she developed persistent pain so severe she went to the emergency room of the hospital. On June 14 a mass was removed from her kidney. It had not spread and she was given a good prognosis. She was, however, very worried about a relapse and came to talk about the use of vitamins. I advised her to take vitamin C 8 g, niacinamide 1 g, B complex (50), selenium 400 mcg, and beta carotene 50,000 iu. One year later she was normal. No recurrence was found at her annual check up. She was well September 1996.

Born in 1988, he was first seen in June 1992. In February 1991 his father noted a mass on his right side. Wilms tumor was diagnosed and the right kidney mass was removed plus about 5 inches of intestine. He also had 5 spots in his lungs and was started on chemotherapy, one session per week for twelve weeks. In May 1991 two masses were removed from his lungs and he was then given radiation for two more still present. He was very small, weighing 22 pounds, his sense of taste was poor, and he had no appetite. His parents had to force him to eat. He had white areas in his finger nails, indicating a serious zinc deficiency. I advised his parents to start him on ascorbic acid. He could not swallow anything and so had to be given chewable vitamin C. They were able to give him 500 mg daily. He was also given liquid zinc sulfate 30 mg daily. On 11 January 1993 he was normal. His mother told me he had had a recent cancer check up six months following his last chemotherapy and there was no evidence of any recurrence. She added that his appetite became normal only after he started taking the zinc solution. On 14 February 1994 a CT scan showed another tumor in the left lung. On 6 July 1994 the tumor had not grown any more and appeared a little smaller on examination. He was taking 8 g of vitamin C plus the other vitamins. I added pycnogenol 40 mg o.d. to his program. He felt well and appeared normal. In June 1996 he was normal. He was clear of cancer. — Abram Hoffer

Patients Still Alive Five Years and More

Born in 1953, she was first seen in July 1990. During October 1989 she felt a lump in her right axilla which was cancerous. She received radiation for three weeks, two per week, and on 19 January 1990 had a lumpectomy. After that she received chemotherapy once every month for four months. She had heard Dr Linus Pauling lecture on cancer and vitamin C and wanted to start on a proper preventive program. She was advised to take the following nutrients: ascorbic acid 4 grams t.i.d., niacinamide 0.5 g t.i.d., selenium 200 mcg b.i.d., B-complex SOs od, vitamin E 400 iu od, Chromium 200 mcg od. In July 1996 she was well.

Born in 1914, she was first seen in January 1990. This patient first came to see me in July 1980 in the hope something could be done about the onset of sudden blindness of her right eye. She had lost vision in her left eye some twelve years earlier, again very suddenly.

When I saw her again in January 1990, she reported she had been diagnosed with breast cancer in early December 1989. She had remained on the original vitamin program only two months, not being able to follow it because of her husband's illness and eventual two years later, and because she had been traveling and had herseW also been ill. She had been legally blind for many years but still lived alone with home help, was independent, and was able to get around.

Surgery, radiation, and chemotherapy had been recommended for her, but she was opposed to any standard treatment. She had no pain. She had started on Essiac and was on vitamin C 4 grams per day. I recommended the following program: ascorbic acid 4 grams t.i.d., niacinamide 500 mg t.i.d., B-complex 50s od, selenium 200 mcg t.i.d., beta carotene 25,000 iu per day, zinc citrate 50 mg od, cod liver oil 2 capsules per day, evening primrose oil 2 capsules per day, germanium 1 tablet b.i.d., vitamin E 800 iu per day.

She was seen again inJune 1990. She was on ascorbic acid 16 grams per day plus the rest of the program. She had no pain, her weight was steady, and she was not depressed. Beta carotene was increased to 75,000 iu t.i.d.. In August 1990 she reported she was following the entire program, the lump was getting smaller, and she felt well, although she was still concerned over her blindness. In November 1990 she reported she planned to get chelation therapy and that the lump was smaller. She telephoned in April 1991 to discuss a social problem she was having, and called my secretary in December 1991 to report she was doing well; she was concerned, however, that her family physician, who herself had been receiving standard therapy for breast cancer for the past year, was not doing well at all and had given up her practice.

She called in early February 1992 to report she was doing well. She had sold her house and was moving to an apartment in a nearby community. On 30 November 1992 she was free of cancer but was having other physical problems which had put her into hospital several times over the summer. On 4 August 1993 she was free of cancer. In July 1996 she was well.

Born in 1948, she was first seen in March 1990. This patient had a lumpectomy, right side. She had detected a lump some time before that, noticeable just before her periods, and her breasts were tender. Mammogram suggested a cyst but biopsy was positive for cancer. Further exploration was suggested and radiation was considered. She had been under a lot of stress over the past year. I started her on the following program: ascorbic acid 4 t.i.d., chromium 500 mcg per day, niacinamide 500 mg t.i.d., B-complex S od, pyridoxine 100 mg od, zinc citrate 50 mg b.i.d., selenium 200 mcg t.i.d., magnesium oxide 420 mg od, calcium 500 mg per day, evening primrose oil 3 capsules per day, beta carotene 25,000 iu per day, cod liver oil 3 capsules per day, mm E 800 iu per day, folic acid 5 mg b.i.d.

She reported on 30 May 1990 that she had had a lumpectomy April 12th and one node was positive. She had just started chemotherapy and would be receiving it every three weeks. She would also receive radiation between chemotherapy sessions. She felt great and had come through the operation easily. At that time her beta carotene was increased to 25,000 iu t.i.d. and she was on sodium ascorbate 12 to 15 g per day.

On 13 February 1992 she was normal, on the entire program, was cheerful, and there had been no recurrences. On 17 November 1992 she was well and cheerful and remained well in February 1996.

Born in 1945, she was first seen in May 1989. Following her annual medical checkup when she had a mammogram, a tumor of the left breast was discovered. It was less than 2 cm in diameter, and she received a lumpectomy with axillary dissection in early March 1989. There were no positive nodes (stage 1). She had never been ill and was quite surprised when this happened. Her surgeon had recommended radiation after surgery, but no chemotherapy was suggested. Because she was tense after her biopsy, she was given valium, to which she had a very severe reaction lasting 7 days, including phlebitis, joint pains, etc. She had to receive two different types of antibiotics in order to deal with this reaction because it was thought she might have some kind of hidden infection.

She had heard about the use of nutrition and supplements to enhance the immune system, and wanted to do what she could to help herself. I suggested she start on the following program: ascorbic acid 4 grams t.i.d., niacinamide 500 mg t.i.d., B-complex 50s od, vitamin A 20,000 iu per day, beta carotene 20,000 iu per day, zinc citrate 50 mg per day, magnesium oxide 420 mg od, selenium 200 mcg b.i.d., vitamin E 400 iu b.i.d. She was to continue eltroxin 125 mcg per day.

On 21 June 1989 she reported she had more energy was no longer exhausted, and could tolerate the whole program. She had some pain in the left axilla. It was decided she did not require radiation. Kelp 1 g b.i.d. was added to her program. On 18 February 1992 she reported she was well and was following the whole pr~igmm. She was cheerful and had in the meantime remarned. In May 1996 she was well.

Born in 1946, she was first seen in May 1990. In 1986 this patient developed a lump in her left breast which was biopsied and found to be benign in February 1987. However, a second lump formed beneath the scar tissue, and in July 1989 was found malignant. She was given a lumpectomy, followed in September 1989 by mastectomy. Four nodes were positive of 17 examined. In October 1989 she started chemotherapy every three weeks. In January 1990 she had 16 radiation sessions and felt very sick thereafter, having her last treatmentJanuary 25. After that she improved but she still lacked energy.

She was started on the following program: ascorbic acid 4 grams t.i.d., niacinamide 500 mg t.i.d., B-complex SOs od, vitamin E 400 iu b.i.d., beta carotene 25,000 iu t.i.d., cod liver oil 6 capsules per day, selenium 200 mcg t.i.d., zinc citrate 50 mg od, cal/mag 2 tablets b.i.d., folic acid 5 mg od, Slow-K 600 mg b.i.d. Late in November 1990 she reported she was doing well, was still following her diet, but had reduced her vitamin intake. She felt well, was working full time, keeping very busy, and she was optimistic. She contacted me again in December 1991 to report she was very well and free of cancer. She remained on her vitamin program. On 31 March 1993 she wrote that there had been an increase in tumor markers and that she had been started on tamoxifen. In May 1994 she wrote that she was well and working. Her tumor blood marker was slightly elevated. In May 1996 she was well.

Born in 1936, she was first seen in December 1988. In March 1988 a lump was detected in her right breast which was positive on biopsy; there also had been some spread to the glands on that side. She refused surgery, putting herself, instead, on a very good program including herbs. Later she went to the Hoxey Clinic in Mexico for a vaccine treatment, which did not help, and eventually went to the Gerson Clinic in Mexico for three weeks of treatment. The cancer continued to grow and eventually her arm was three times its normal size, with the breast very large and the tumor very prominent. She then consulted a physician who started her on IV vitamin C 50 grams per day, gradually increasing it to 75 grams per day. Apparently, the swelling in her arm and breast disappeared soon after starting the injections, and the tumor began to recede very quickly. She also had had one chemotherapy treatment about that time. Bone scan was negative. She was healing quite well and both she and her husband were quite optimistic.

She was on a daily regimen of vitamin E 1,500 iu, vitamin A 4,000 iu, vitamin D 400 iu, B-complex 25s, kelp 4 tablets, and selenium 200 mcg. She was not able to take more than 9 grams per day of vitamin C orally because of diarrhea, and was also taking B-12 injections 1 mg every three weeks. I modified her program as follows: to continue her IV ascorbate, add calcium ascorbate 4 grams t.i.d. if possible, niacinamide 500 mg t.i.d., beta carotene 20,000 iu per day, selenium 200 mcg t.i.d., magnesium oxide 420 mg per day.

In July 1989 she reported she had had her last chemotherapy in June, and that she had not been too sick on treatment days. She was on intravenous ascorbate 25 grams once per week as well as 12-16 grams per day orally. She had had one radiation treatment, her hair was coming back, the hard tissue she had in her axilla was clearing, and her mood was good. Her program was modified to niacin 50 mg t.i.d., vitamin E 800 iu per day, selenium 200 mcg b.i.d., beta carotene 50,000 iu per day, vitamin C 20 grams per day, evening primrose oil 2 capsules per day, and lecithin 1.2 g per day. Early in 1991 she started ozone therapy. When I spoke with her on 20 February 1992, she was still well with no sign of any recurrence. On 12 January 1994 she was still well and still receiving ozone treatments. A recent check up showed no evidence for any cancer. In July 1996 she was well.

Born in 1936, she was first seen in March 1989. The previous year, about one month after detecting a lump in her right breast, she received a radical mastectomy. No nodes were involved, but there had been some spread to the vascular system, and she was not sure if it had been adherent to the skin. After that she received six months of chemotherapy, one treatment every three weeks, followed by 22 radiation treatments, the last in May 1988. She had been following a vitamin program of her own for some time to try to prevent a recurrence.

She had gone through a difficult period with digestive proW lems about five years before, to the point she consulted the Mayo Clinic. She ~was treated by food avoidance to try to pinpoint her food allergies and this was not a major problem when I saw her. She did have hot flashes since her radiation and complained that herjoints had been aching.

I started her on the following program: ascorbic acid 4 g t.i.d., niacinamide 500 mg t.i.d., B-complex SOs od, vitamin E 800 iu per day, pyridoxine 100 mg per day, vitamin A 10,000 iu per day, selenium 200 mcg t.i.d., beta carotene 20,000 iu per day, cal/mag (500 mg calcium/250 mg magnesium) per day.

On 20 February 1992, she reported she was well, with no sign of any recurrence. Her mood was good. In July 1996 she was well.

Born in 1941, she was first seen in January 1989. In October 1987 this patient developed a lump in her left breast, which examination and mammogram indicated was cystic. She had had problems with the breast for the previous 12 years. In 1988, because the cyst persisted, it was aspirated and found negative, but later biopsy indicated she was positive for cancer. She received a lumpectomy on 1 December 1988; all glands were negative. It was recommended that she have chemotherapy because of estrogen sensitivity, but she was loath to do because of possible side effects, especially on her eyes, and she had not yet made a decision.

I suggested she start on the following: calcium ascorbate 2 grams t.i.d., ascorbic acid 2 t.i.d., vitamin E 400 iu per day, B-complex SOs od, niacinamide 500 mg t.i.d., beta carotene 20,000 iu, calcium 1000 mg per day, magnesium 500 mg per day, and zinc citrate 50 mg od. In March 1989 she was on the whole program and was receiving chemotherapy every four weeks and would receive a total of 9. Her oncologist told her he was pleased she was on a vitamin program. On 23 March 1992, the family doctor who had referred her to me indicated she was well and had moved to Vancouver. InJanuary 1996 she was well.

Born in 1955, she was first seen in July 1989. In December 1988 she became aware of soreness of the right nipple. She became pregnant, but on 4 May 1989, the breast became red, hard and swollen, with a large lump. She was examined by ultrasound and placed on antibiotics for 30 days altogether, first on ampicillin, then on cloxicillin, without any improvemeht. this time also her skin became kind of puckered. Biopsy revealed an adenocarcinoma; one lymph gland was involved. The tumor was mobile without any adhesion to skin or underlying tissues.

Shortly after that she received a therapeutic abortion, having been advised that carrying the fetus to term might cost her her life. The tumor appeared to be growing very quickiy. She had two young children at home. She was then started on chemotherapy, having received 3 or 4 treatments by the time I saw her. She was on a variable schedule, and after the first set of chemotherapy it was planned to give her four weeks of radiation therapy, followed by another 12 weeks of chemotherapy. She had few ill effects from the chemotherapy.

I started her on the following program: ascorbic acid 2 g t.i.d., calcium ascorbate 2 g t.i.d., niacinamide 500 mg t.i.d., B-complex SOs mg od, folic acid 5 mg b.i.d., beta carotene 20,000 iu per day, selenium 200 mcg b.i.d., vitamin E 400 iu b.i.d., zinc citrate 50 mg od, kelp 3 tablets per day, magnesium oxide 420 mg per day, cal/mag 2 per day, and coenzyme Q10 30 mg t.i.d.

On 31 August 1989, she reported she was able to follow the whole program. She was receiving radiation. She felt fine and her mood was good. I heard from her again in December 1990, and she was still doing well with no recurrences. On 1 November 1992 she was normal and planned on becoming pregnant again. In July 13, 1993 the cancer recurred with lesions in both lungs, mostly at the base. She was given taxol and cisplatin. On 16 December 1993 she had nearly completed the treatment. She felt much better and was optimistic. I then advised her to increase her Q10 to 320 mg daily. She was still on the vitamin program.

On 4 March 1996 she told me several metastases had been found in her brain, for which she had just completed radiation treatment. Her mood was good. I suggested she add bovine cartilage 9 g daily to her program, melatonin 21 mg od, flax seed oil, 2 tablespoonfuls. In September 1996 she was alive.

Born in 1943, she was first seen inJuly 1988. AroundJuly 1985 she detected a lump in her breast. In November 1985 she had a modified radical mastectomy. Three nodes out of 12 were positive. Following that she was given 6 chemotherapy sessions over a 9 month period and 16 radiation treatments over a period of 3 weeks. She had a minor radiation burn on her skin. She consulted me in order to find out how she could decrease the chance for a recurrence.

I advised her to take ascorbic acid 6 g, niacin 1.5 g, B-complex 50s, folic acid 5 mg b.i.d., zinc gluconate 50 mg, vitamin E 800 iu, beta carotene 20,000 iu, selenium 200 mcg t.i.d., and thyroid 60 mg, all daily. On 4 July 1994 she was well and was still following this program. InJuly 1996 she was well. — Abram Hoffer

Case Histories of patients alive five years or more

Born in 1927, he was first seen in December 1985. In 1978 he had begun to suffer abdominal pain and constipation from diverticulosis. He hemorrhaged in December 1986. He came to see me first in April 1985 complaining of severe anxiety and tension. His whole body was rigid from tension as if he was surrounded by body armor. I modified his diet to remove all free sugars and added ascorbic acid 1 g t.i.d., niacin 1 g t.i.d., vitamin E 400 iu b.i.d., zinc sulfate 220 mg od, and dolomite 2 tablets t.i.d. He also came to see me regularly for psychotherapy. On 19 December 1986 carcinoma of the colon above the transverse and sigmoid area was diagnosed. The tumor and some of the colon was removed. I increased his ascorbic acid to 12 g daily and added 500 mcg of selenium. In February 1987, no tumor was evident on colonoscopic examination and there were no polyps. He was free of anxiety. He then stopped taking the nutrients. InJuly 1987 he became constipated and again began to follow the regimen,, increasing his ascorbic acid to 25 g daily. On 28 March 1988 he was well; on 31 December 1995 he was alive and well and was free of anxiety, tension, or depression.

His wife, Case # 677, born in 1936, was found to have cancer of the ovaries. A large ovarian growth was removed in September 1995. They then went to New York, where she had relatives, and attended Dr N. Gonzalez. She was very concerned because she thought the cancer had been moving very quickly from a time late last January when nothing could be felt until the present when a large size tumor was discovered. She refused to accept chemotherapy. Her husband remained well during this very difficult period. In the fall of 1996 she suffered a recurrence but is still receiving complementary therapy.

Born in 1952, he was first seen in April 1982. Early in 1981 he suffered stomach problems with some rectal bleeding. In December 1981 he was discovered to have cancer of his colon, the transverse section, which was resected. The tumor had perforated the bowel and was infected. Some of his spleen was removed, but there had been no spread. I advised him to take ascorbic acid 12 g, B-coinplex-100, vitamin E 400 iu, selenium 400 mcg, zinc sulfate 220 mg, and calcium magnesium 6 tablets, all daily. In April 1988 his spleen had regenerated. On 23 October 1992 he was normal and on minor vitamin supplements. After 11 years he was still well and was removed from our follow-up list.

Born in 1922, she was first seen inJuly 1981. In 1971 a large fibroma had been removed. In 1973 she suffered from repeated hemorrhages with her periods. In 1977 she had a small stroke which left her for a long time with right-sided weakness and her thinking was fuzzy. She had suffered a lot of family stress. She was divorced from a schizophrenic husband and lived with her brutal addicted son who, a few days after I saw her, blackened her eye. I advised her to start on niacin 1.5 g, ascorbic acid 1.5 g, and zinc gluconate 100 mg and discussed her relationship to her son. On 24 September she was better and stronger.

However, in October 1982 she had again been injured by her son. I increased her niacin to 2 g, adding pyridoxine 100 mg and folic acid 5 mg. In December 1982 she was again much better. On 12 December 1983 she told me her son had at last moved away. She was very weak. In February 1984 she was depressed, but it was not as severe as her depression the year before.In May 1985 she had trouble with her vision from cataracts and they were removed.

In October 1986 she was found to have cancer of the bowel which was resected. I increased her ascorbic acid to 12 g, changed niacin to inositol niacinate 1.5 g, and added selenium 400 mcg. In December 1986 she required further abdominal surgery to repair some damage. There was no evidence of recurrence. In May 1989 the cancer had occluded her bowel. This was resected and she was left with a colostomy.

On 22 November 1990 she told me she had not been able to follow the full program. I advised her to take ascorbic acid 8 g, niacin 2 g, selenium 400 mcg, vitamin E 800 iu, and Q10 90 mg, daily. I doubt she was able to follow this program. She developed congestive heart failure and was given digoxin but was not able to follow the correct dose. She died 11 August 1992. The coroner concluded she died from congestive heart failure. She had excessive amounts of digoxin in her blood. At autopsy she was found to have adeno carcinoma of the peritoneum with a left hydronephrosis. The cancer had recurred but she did not die from it.

Born 1917, she was first seen in April 12 1989. InJuly 1986 one foot of the transverse colon was resected. There was by then some extension into her liver. Before the operation, there had been few if any symptoms but it was detected on physical examination. Soon after she placed herself on a moderate-dose vitamin program, including 1750 mg of vitamin C daily. She came to see me because she was concerned whether this program was adequate. I suggested since there was no evidence of recurrence that she follow the program with a few changes as follows: vitamin C 1750 mg od, niacin 0.5 g t.i.d., selenium 200 mcg b.i.d., B-complex 50 mg od.

One month later she found that she could not tolerate the niacin flush, so the niacin was replaced with niacinamide 0.5 g t.i.d. On 7January 1992 she was normal and her mood was good. She was still on the same program. On 17 May 1993 she was well, even though she was not following the program and had forgotten what vitamins she had been taking before. In April 1996 she was again well.

Born 1939, she was first seen in October 1990. In May 1990 this patient noticed some blood in her stool, but nothing positive was found. She went to Europe in mid-July and developed bladder pain. On return home, investigation, including barium enema, revealed cancer of the colon. Some of her bladder was removed; there was no extension into it. The colon was resected and 4 out of 18 nodes were positive, but apparently there were no other metastases. She started on chemotherapy, having a very severe reaction to the first one: her white blood count went down to 30 and her neutrophils to 16. After that they did go up, but it was necessary to watch the chemotherapy very carefully. It was considered unusual to react badly to that type of chemotherapy. After the last session before she was seen here, she developed a high fever.

Before she was diagnosed with cancer she had been very healthy, except that she had been constipated for several years, requiring constant treatment with Agarol, a laxative. She was very physically fit and was active in sports.

She was started on the following: ascorbic acid 4 grams t.i.d., Niacinamide 500 mg t.i.d., B-complex SOs od, vitamin E 400 iu b.i.d., cod liver oil 2 capsules per day, beta carotene 25,000 iu t.i.d., vitamin K S mg od, selenium 200 mcg t.i.d., cal/mag 3 tablets per day, magnesium oxide 420 mg per day, and zinc citrate SO mg per day.

She telephoned in November 1990. She was on calcium ascorbate 6 grams per day, having been told by someone she did not require more. I asked her to increase it back up to 12 grams per day. She was no longer constipated, her mood was good, and she planned to discontinue chemotherapy. December 1990 she felt great, had no problems, was not constipated, and felt normal. She telephoned in March 1991 to state she had been skiing and developed diarrhea at 7,000 ft elevation but not at the lower levels. She had a lot of energy, but occasionally got short of breath, which could come at any time. She was still on chemotherapy. On 12 February 1992 she reported she was normal. There was no sign of cancer at her last check up, and she was following the full program. She was very cheerful. In October 1996 she was well.

Born 1934, she was first seen in July 198S. In December 1984, cancer had been resected from her sigmoid colon. Out of 7 glands, one had metastases. Then she was given 20 radiation sessions. In addition she had been depressed following a series of marital problems, for which she was receiving psychotherapy. I advised her to stay on her diet, which consisted mostly of ensure mixed with yogurt, but to add one new food each week as a test of her tolerance. She also was advised to take ascorbic acid 12 grams daily, niacinamide SOO mg t.i.d., B-complex (100) od, selenium 400 mcg daily, zinc gluconate SO mg od, and calcium and magnesium tablets 4 daily. I gave her mycostatin for yeast infection. One month later she reported she could only take 1.S grams of vitamin C daily because of severe diarrhea. She was able to tolerate the rest of the program. She felt much better and was not as confused as she had been.

On 24June 1992 she was normal. This was reported to me by her son whom she had sent to me for treatment. She was still following the vitamin program. In December 1996 she was well. Her three last sigmnoidoscopic examinations were normal.

Born in 1917, she was first seen in November 1987. Eight years before I saw her she was given a colostomy for colon cancer. In 1984 she suffered from a bleeding ulcer. Apart from a few other complaints unrelated to her colostomy, she got on well but she was concerned about a possible recurrence and came for advice. I suggested she follow the following program: ascorbic acid 3 g, niacin 1.5 g, B-complex (SO), selenium 200 mcg, vitamin E 400 iu, and calcium maguesium two tablets, all daily. She was seen several times, the last in February 1992 for other problems. On 10 November1992 she was free of cancer and was still on the program.

On 13 December 1993 she told me she had had an hysterectomy one month earlier because a small tumor was found, Stage 2, after her second d & c. It had apparently not spread. She was depressed over this second assault on her by the cancer yet her colon remained normal. I increased her ascorbic acid to 6 g, increased her folic acid to 15 mg, and added Q10 150 mg daily. For her depression I added an antidepressant. On 10 February 1994 she reported she had one long radiation session to her abdomen. I have continued her on an antidepressant and added Q10 300 mg daily in October 1996. — Abram Hofftr

Out of 16 patients in the study with leukemia, 10 were alive one year, 9 were alive 2 years, 5 were alive 3 years, 4 were alive 4 years, 3 were alive 5 years, and 6 are still living.

Born in 1920, she was first seen in August 1983. In 1958 this patient was treated for goiter with radioactive iodine, after which she needed thyroid hormone and calcium to prevent severe muscle cramps. In March 1983 chronic leukemia was found. When I saw her, she also complained that she had severe pain in her hands and feet, swollen fingers, a dry scaly skin, and angina not related to effort. I advised her to add ascorbic acid 1 g t.i.d., niacin 1 g t.i.d., pyridoxine 250 mg od, zinc gluconate 100 mg od, and flax seed oil 1 tablespoonful od. Two months after her blood picture was much better and she felt better. The pain had diminished. After another month her platelet count increased to about 250,000, her white blood cells count decreased from 11,200 to 9,100, and her hemoglobin increased from 13.4 to 14.0 G. A CT scan showed that liver and spleen were enlarged. By April 1988 she was much better. Her liver and spleen were normal as was her blood count but her feet still hurt. She felt good and was cheerful. She died in December 1989, age 69.

Born in 1924, he was first seen in November 1987. Following mild fatigue present for 1.5 years, hairy leukemia was diagnosed in February 1987. After I saw him, he started on ascorbic acid 4 g t.i.d., niacin 0.5 g t.i.d., folic acid 5 mg od, selenium 200 mcg t.i.d., beta carotene 20,000 i.u. od, zinc citrate 100 mg od, a vitamin B-complex SOs preparation od, magnesium oxide 420 mg od, and cod liver oil capsules t.i.d. He started chemotherapy in 1988, completing the series in July. By April 1989 he was well and taking only ascorbic acid 8 g daily. When he was first seen in November, hemoglobin was 11.6, then by April hemoglobin was 12.2, wbc was 2,900, platelets were 86,000, and there were 15 percent circulating hairy cells. By February 1989 his hemoglobin was 14.2, his wbc 6,000, and there were no hairy leukocytes. He was still well in October 1996.

Born in 1916, he was first seen in June 1991. He had a triple coronary bypass 12 years earlier and later had a pacemaker inserted. In August 1990 chronic leukemia was diagnosed. He started himself on a mixture of vitamins and minerals. His wife died the previous November from cancer of the breast. In February 1991 he suffered a heart attack and was placed upon medication. When I saw him, I advised him to follow the program he was on, but to include vitamin C 12 g, niacin 1.5 g, pyridoxine 250 mg, vitamin E 800 iu, selenium 600 mcg, zinc citrate 50 mg, and beta carotene 25,000 iu, all daily. On May 20 1992 I added 1-lysine 2 g daily. In June 1992 his white cell count was stable, around 10 g/L. On 28 January 1.993 his blood platelets were low, but the rest of the count was normal. His mood was good. I added folic acid 10 mg and vitamin B-12 1 mg daily to his program. He was still well in July 1996.

Born in 1912, she was first seen inJuly 1986. This patient came to see me because of her severe arthritis present for 13 years. She had started herself on a multivitamin program and felt better but wanted advice on how.to improve this. She then told me she had chronic lymphatic leukemia, her wbc being 16.7 in July 1984 and remaining at that level since. She had her spleen, gall bladder, and appendix removed. I added niacinamide 1.5 g daily for her arthritis. She was already taking vitamin C 6 g, selenium 200 mcg, and other nutrients. In February 1987 I increased her niacin to 4 g daily. By March 1988, she was free of pain. In May 1987 she had surgery to remove a small bowel blockage and was given a temporary colostomy. I saw her in September 1989 and she~was getting on very well. When seen last by her general practitioner at the end of January 1992, her mood was good, but she was still having some difficulty with her arthritis. She was still on her vitamin program. She was still well inJuly 1996. — Abram Hoffer

Born in 1920, she was first seen in April 1984. On 2 November 1983 she had suffered terrible flu, a cold, a cough for four months with increasing amounts of sputum, weight loss and lethargy. On examination there was reduced air entry into the right upper lobe and dullness to percussion. The X-ray revealed collapse of the right upper lobe. A mass was felt during mediastinoscopy and fluid was aspirated containing pus. The surgeon thought it was a bronchiogenic carcinoma that had broken down. Later the surgeon saw a tumor on the right side which had totally occluded the right upper bronchus and had extended to the lateral wall of the right main bronchus and to a level below the carina. The pathological report showed a poorly differentiated squamous cell carcinoma. This was considered non-resectable because it was unlikely she would tolerate the procedure. Her prognosis was considered poor because the tumor would probably not resolve completely and the possibility of distant metastases was high. She was told she could expect to live about one year.

On 3 January 1984 she started to receive cobalt irradiation until 14 February 1984, receiving 20 sessions. A month later she had an upper respiratory infection and was giVen antibiotics. On 24 April 1984 she was started on the vitamin regimen including vitamin C 12 g, niacinamide 1.5 g, zinc sulfate 220 mg, vitamin E 800 IU, selenium 200 micrograms and a multimineral preparation.

In March 1986 she complained of intermittent claudication. She was high in cholesterol and one artery was clogged in her right leg. I added inositol niacinate 1.5 g, calcium 1,000 mg, and magnesium 500 mg. A month later she was able to walk four blocks. In January 1993 she had a mild stroke, so mild that after intensive investigation in hospital the diagnosis still was uncertain, but she was left with mild speech impairment which cleared in a few months. On 24 December 1993, there was no recurrence of her cancer but both legs were badly swollen and she was waiting for a bed for investigation. Her mood had been good until this had happened over the past few weeks. Later in December 1993 she suffered a stroke which left her speech impaired. Mter that she had three episodes of flu. She died 25 January 1994 at age 73 just three months before her tenth anniversary of having first seen me.

Born in 1927, she was first seen in March 1981. In December 1980 she had experienced sharp right-sided chest pain. An x-ray showed a large mass in her right lung. A bronchoscope in December 1980 showed a visible tumor involving the lateral wall of the right lower lobe bronchus and extending into the right upper lobe bronchus and occluding the oriface of the superior segment of the right lower lobe. She had a small oat cell bronchiogenic carcinoma. She also had an ill-defined area in the left tempero partietal region. She was considered inoperable and she was given radiotherapy to her brain starting in January 1981, and chemotherapy which was completed inJune 1981. This was then followed by radiotherapy to the right lung completed inJuly 1981. A note in the cancer clinic report states, "This lady elected to go ahead with chemotherapy. She understands it's palliative and not curative.

On 4 March 1981 I advised her to take ascorbic acid 12 g, niacinamide 1.5 g, a B complex preparation containing zinc. At the end of 11 years there has been no recurrence. Her memory is very poor, probably due to the radiation to her head. She was on the total vitamin program probably not more than one year. March 1992 she was well and was taken off the follow up program. She was still well in October 1996.

Born in 1933, she was first seen in September 1987. The middle and lower right lung had been removed in August 1985. She came to see me depressed and concerned about a recurrence. Her depression was being treated with an amine oxidase inhibitor, which she thought could have been a factor in the development of her cancer. I advised her that this was unlikely and to start the following vitamin program: ascorbic acid 4 grams t.i.d., niacin 500 mg t.i.d., folic acid 5 mg b.i.d., B-complex SOs t.i.d., zinc gluconate 50 mg od, and selenium 0.200 mg b.i.d. On 31 December 1989 she was well and following the program, except for the niacin. She had flushed too much on niacin and had reduced the dose to 250 mg b.i.d.. She died 1 November 1990.

Born in 1916, she was first seen in October 1990. Early in 1990 this patient developed a lump in a left neck gland. At biopsy on 1 May 1990, an adenocarcinoma was found but there was no primary. In June the tumor was resected, but because of its proximity to the jugular vein could not be entirely removed. Following that she received 10 radiation sessions over a two-week period, and she was on tamoxifen. About the same time she started herself on a vitamin program which she had been following for three months before I saw her, and she felt a lot better. She had been taking vitamins for many years. She had a second lump develop on the right side of her neck but it had stopped growing and may have started to recede, as had some post-radiation nodules. She had a cough she found troublesome which she thought might be due to allergies.

On her own she had been taking: germanium 150 ug od, vitamin A and D containing 10,000 IU of A, evening primrose oil 1 gram per day, EPA 1 gram per day, vitamin E 400 IU per day, beta carotene 10,000 IU t.i.d., coenzyme Q10 30 mg per day, a super mineral preparation, B-complex 75 mg od, B-6 125 mg od, quercetin 1 gram per day, selenium 200 mcg t.i.d., zinc citrate 50 mg od, vitamin C 24 grams per day. I modified her program only slightly, changing her beta carotene to 25,000 IU per day, the selenium to 200 mcg b.i.d., and adding aspirin 325 mg od.

On 3 December 1990, she reported all the lumps in her skin were gone. In April 1991 her daughter reported that her mother had been in hospital in Hawaii for seven days after developing fluid in her chest and abdominal cavity. The fluid was drained. A primary was discovered in the lower lobe of her left lung. In hospital for one month a lot of fluid was drained from her abdomen and chest. She had been given antibiotics and 35 radiation treatments to her chest and neck but had been off her vitamin program. After discharge, she resumed her nutrient intake. ByJuly her strength was returning, her appetite was okay, and her weight was steady.

Late in November 1991 she reported she was better, but that she needed afternoon naps or she tired. She was able to tolerate ascorbic acid 16 grams per day. Her last CT scan was clear, she had no surface lumps, but had a tiny nodule on her neck. Her mood was good, she was very cheerful and felt really good. In September 1992 she still coughed and had some sputum, but she was otherwise well. In November 1992 she was still well and was on her program. Again on 23 November 1993 she was well. In April 1992 two nodes of cancer were found in her chest. She received more radiation and since then has been well. Her mood was good and she was optimistic. She was still on the entire program. On 15 December 1993 she increased the coenzyme Q10 to 240 mg daily.

On 22 March 1994, she was in hospital. She had become short of breath. One liter of fluid was removed. After this was done she was found to have two lesions in her left lung. She was to receive more radiation. Her mood was good. While in hospital she remained on her nutrient program. She died 24June 1994.

Born in 1929, she was first seen in July 1991. In August 1990 she began to cough. On examination she had a large lesion, the size of a large orange, in her right lung which was attached to bone. She was given 20 radiation treatments which shrank the tumor. Three months before I saw her she developed pain in her back from a hairline fracture. The last x-ray examination before I saw her showed the tumor had regressed. I advised her to take ascorbic acid 12 g, niacinamide 1.S g, B complex-SO, folic acid 10 mg, vitamin E 1200 IU, selenium 1000 mcg, beta carotene 100,000 IU, boron 3 mg, and manganese 15 mg, all daily. On December 31 she reported her x-ray at the end of October showed no tumor, only some scar tissue. She was able to take 9 grams of vitamin C and had decreased the amount of some of the other vitamins and minerals. InJuly 1992 she had occasional back pain and was still on the program. She was alive inJuly 1996.

Born in 1932, she was first seen in June 1991. In May 1991 she suffered the flu and cough. On routine x-ray a shadow was observed in her lung which had apparently been there one year before. A biopsy was positive. At first she refused to have surgery but later agreed to it in July. Three years earlier she had a myocardial infarct, later angina, and inJanuary 1989 she had angioplasty. She had started to take vitamin C 6 grams per day, coenzyme Q10 200 mg, and beta carotene. I advised her to increase the vitamin C to 12 g, to add niacin 1.S g, B complex-SO, beta carotene 7S,000 IU, vitamin E 800 IU, selenium 600 mcg, zinc citrate 50 mg, and folic acid 10 mg, all daily. On 11 June 1992 she was well and felt good. On 22 February 1994 she was getting on well. Again in June 1996 she was well.

Born in 1943, she was first seen March 1992. In 1974 she had a radical mastectomy followed by iS sessions of irradiation. About mid-1988 a lesion was found in her right lung and the middle lobe was removed. Two years later it recurred but was very slow growing. I advised her to take ascorbic acid 12 g, niacinamide 2.0 g, B complex 50, selenium 600 mcg, beta carotene SO,000 IU, vitamin E 800 IU, and zinc citrate 50 mg. On 31 December 1992 she was well and was on the full program.

In March 1994 she discovered cervical nodes, and on 16 March 199S she was very ill. Her tumor in her lung was enlarging rapidly. She had more radiation. Medication given caused perforation of her intestine. She had lost 40 pounds and was no longer able to follow the regimen. She died 17 March 199S. — Abram Hofftr

Cases Alive Ten or More Years

Born in 1959, he was first seen in March 1984. On 24 December 1982 he complained of acute left upper quadrant pain. His white blood count was 15,000 and he had some fever. He recovered in a few days. On 11 February 1983 he was found to have a huge abdominal mass on the left side. After a few days he left hospital before the investigation was completed but came back a few days later. A few days later he was started on chemotherapy, and by 3 March 1983 the mass was smaller and softer. But his oncologist recorded that "he presents with an incurable condition which undoubtedly in the near future will take him away." He was then diagnosed as having paranoid schizophrenia with retroperitoneal lymphoma.

On 27 March 1984 I examined him. He was very anxious and worried about his lymphoma. He was then not showing any schizophrenic symptoms and signs. I started him on ascorbic acid 12 g, niacin 1.5 g, B-complex 75s, twice daily, and selenium 150 mcg, all daily. On 4 February 1985 he was admitted to the psychiatric ward. This time he complained of visual illusions, he had a few paranoid delusions, and was very depressed. He was admitted again in March 1985, and by then I had rediagnosed him with schizophrenia, paranoid. He was started on a parenteral slow release tranquilizer because he was not very good at following his medication regimen. He was admitted for the last time July 1991 for two days following several experiences with LSD. He had had many admissions over the previous 6 years. For his schizophrenia and to prevent a recurrence of the lymphoma, he took niacin between 3 and 12 g daily, ascorbic acid between 3 and 20 g daily, and any medication he needed using antidepressants or tranquilizers.

At the end of 1993 he was free of his lymphoma but his mental condition was unknown. When last seen he was on niacin 6 g and ascorbic acid 20 g, daily. He was alive 3OJune 1996, but I have not seen him for several years.

Born in 1970, he was first seen in February 1984. He became sick in 1979, diagnosed with Crohn's disease. He was given prednisone and stopped growing. His bowel ruptured and required surgery. Two years later he developed Hodgkins lymphoma with the tumors in his abdomen. He was given a 10 percent chance of survival. He received chemotherapy with severe side effects, losing all his hair. He would have had surgery but was too weak. His mother then started him a on a comprehensive dietary mineral vitamin program including laetrile.

I saw him 20 February 1984 and advised him to remain on his program but to include ascorbic acid 3 g, vitamin E 200 iu, selenium 200 mcg, and vitamin A 50,000 iu, all daily. When last contact was made, he had graduated from university and had remained well. He was not following the vitamin program regularly. He continued to improve and was well at 10 years after I first saw him. I took him off the follow-up list. However, on 23 November 1996 I ran into his parents in downtown Victoria. They told me that he is still well and they were very grateful for this.

Born in 1947, he was first seen in January 1982. He was severely depressed. I started him on an antidepressant and on ascorbic acid 3 g and niacin 3 g daily. On 2 December 1982 he was operated for a mass on his back which was found to be benign; however, he did not feel good and the surgical area would not heal. After further surgery his wound began to heal. In May 1983 he began to suffer severe abdominal pain and was constipated. In June 1983 biopsy of his spleen showed a lymphoma, a small cell diffuse lyphocytic lymphoma described as controllable, not curable. He was given cobalt radiotherapy. I increased his ascorbic acid to 12 g, adding selenium 400 mcg, vitamin E 400 iu, and magnesium oxide 840 mg.

In July 1983 he started to receive chemotherapy — adriamyacm, cyclophosphamide, vincristine, and prednisone — receiving six cycles. In February 1984 he was started on radiotherapy, 15 sessions over three weeks. On his own he increased his selenium to 2,000 mcg dally. There were no side effects, but I asked him to decrease it to 1,000 mcg. On 16 March 1984 he had a diffuse mass posteriorly on the left side of his chest wall. He was given more radiation therapy in 15 sessions. On May 22 the mass was gone, but on June 11 it had recurred as a paraspinal mass of the lower left thoracic spine, separate from the previous mass. He was given more chemotherapy and radiotherapy, completed in May 29. By then he had a left sided effusion lymphoma infiltrate. On 25 June 1984 more nodes were developing. The oncologist noted that he "clearly has a progressive disease not being controlled by chlorambucil and prednisone." On 5 July 1984 he received more chemotherapy with a dramatic resolution of the glands. In Augnst 1984, still on chemotherapy, his oncologist recorded that "I can definitely state that this man has persistent incurable malignant disease."

By 24 September 1984 he was free of symptoms and refused to accept any more chemotherapy. On 23 January 1985 a CT scan showed a large right pelvic mass and a second smaller one near the duodenal loop. He was given more radiotherapy to the mass. On 19 April 19 1985 a 2 cm diameter mass appeared in his right leg. This was his eighth recurrence of cancer.

By March 1986 he had recovered. In April 1988 he was well. His oncologist knew he was taking vitamins and was unhappy about this. He recorded 3 August 1983, "I can no longer feel any intra-abdominal mass. Unfortunately, he started on large doses of vitamin C and B vitamins prior to therapy and he is convinced that these are responsible for his good response rather than the chemotherapy." On 31 December 1994 he was well and on the regimen. He is a poet and wrote a poem to celebrate his recovery after he had been given three months of life at the most after he was diagnosed. In September 1966 he was well. This patient is normal, has established a good relationship with a woman he met in Victoria, has a job, and is active in community affairs. During his last visit to me several months ago, I asked him how much vitamin C he had been able to take. He replied that he had been on 40 g daily. He said that he had severe diarrhea and had to sit on the toilet most of the day reading, but that considering the alternative he did not mind. In fact, vitamin C does not produce the usual type of diarrhea common to severe abdominal infections. It simply makes the stools very watery due to retention of water. It is more like a continuous excretion of watery stools but will not cause dehydration if the fluid intake is maintained.

Eight patients were treated. One died after five years. One did not reach five years. Her history is given below. 'The rest are still alive, ranging from 2 to 6 years.

Born in 1950, she was first seen in December 1991. One year before I saw her she developed night sweats. Later she was found to have a mass in her chest and one in her neck. She was given chemotherapy for six months in 21 day cycles. Following that she had one month of radiation. She was very sick during the chemotherapy, was very tired, and developed sores in her mouth. When I saw her, she was much better. On prednisone she had gained much weight. In addition, she was depressed. I advised her to take ascorbic acid 12 g, niacinamide 1.5 g, B-complex 50, selenium 600 mcg, beta carotene 25,000 iu, zinc citrate 50 mg, all daily.

On 11 August 1994 she was normal, but on 16 February 1996 she died suddenly. However, she did not die directly because of her cancer: the cause of death was status post chemotherapy and mediastianal radiation for nodular sclerosing Hodgkins disease given in 1991. Her heart showed Adriamycin-induced cardiotoxicity, with a resulting dilated cardiomyopathy and mural thrombus formation within the right atrium and right ventricle. Perhaps if she had not had this severe toxic reaction to the chemotherapy, she would still be alive today.

Cases Living More Than Two Years

Born in 1922, she was first seen in November 1986. In 1984 she began to suffer repeated episodes of weakness. One year later her glands became swollen and her stools became very pale. In October 1986 she was given a bypass after becoming severely jaundiced. I improved her diet and started her on ascorbic acid 4 g t.i.d., niacinamide 500 mg t.i.d., beta carotene 10,000 iu b.i.d., vitamin A 25,000 iu od, zinc sulfate 220 mg od, and selenium 200 mcg t.i.d. One month later she had been able to increase her ascorbic acid level to 22 g od. In October 1996 she was still well 10 years later.

Born in 1919, she was first seen in July 1978. In May 1978 she developed obstructive jaundice. At laparotomy a 6 cm diameter hard mass was found in the head of the pancreas which totally obstructed her common bile duct. The diagnosis was so certain it was decided not to do a biopsy in order not to increase the chance of metastases. A cholecysto-jejunostomy was performed. After the operation she was informed her prognosis was very poor and that she should get her affairs in order. She had been concerned about cancer for three years following the death of her sister.

She was determined that she would not die. She had read Norman Cousins's book, Anatomy of an illness, where he described his recovery using megadoses of ascorbic acid (intravenously at first, later orally) and laughter induced by watching funny movies. She began to take 12 to 16 g daily plus small amounts of B vitamins. On 21 July 1978 I advised her to increase her ascorbic acid to bowel tolerance levels and to add niacinamide 1.5 g, zinc sulfate 220 mg, and proteolytic enzymes with each meal. She went up to 40 g but one month later was taking only 35 g daily. On 21 February 1979 she told me that a recent CT scan had shown no mass was present. The radiologist could not believe this and repeated the scan with the same results. A few months later another scan showed that her common bile duct was functioning well. She now has two. She remained on the whole program for five years, then decreased the amount of ascorbic acid she was taking. InJune 1996 she was well. This patient told her friends and her co-workers about her recovery. Soon some of them were referred to me and gradually the number of referrals increased. I credit this patient with having brought me into this new field which might be termed orthomolecular oncology. — Abram Hoffer

Of 3 sarcoma patients, one is alive 3 years, the second lived 9 years and died of a coronary at age 80, and the third is still alive after more than 10 years. Twelve patients received total treatment for melanoma. Four died the first year. Three died in the second year, and 5 are still alive over 2 years. All the 6 controls died the first year.

Born in 1908, he was first seen in January 1980. During March 1978 he began to feel a stabbing pain in his left groin. Early in 1979 this was traced to a cancer in his pelvic bone. It was spindle cell sarcoma (neurofibrosarcoma) which was spreading internally. Surgery relieved the pain, but later he was given radiation, completing the series in April. By the end of the year the mass had started growing again. More radiation was not recommended, and he rejected chemotherapy. He was also under severe stress because his wife was dying from cancer. After her death he told his physician that he had nothing much left to live for, that he intended to go to a clinic in Mexico even if it meant blowing his entire estate. I advised him to start on ascorbic acid 4 g t.i.d., niacinamide 0.5 g t.i.d., pyridoxine 250 mg od, zinc gluconate 100 mg od, and a mineral preparation.

A month later he told me he could not tolerate more than 12 g of ascorbic acid daily. I recommended to his referring physician that he give him sodium ascorbate intravenously 2.5 g, 3 times per week. But in that first month a chronic boil (staph) under the tumor on his left leg had healed, he had no edema, and his mood was normal. The radiologist reported in 2 May 1980, "Comparison is made with the previous study of February 7, 1979, which showed an apparent expanding destructional lesion involving the superior ramus of the left pubic bone which was involved with Pagets disease compatible with sarcomatous change of Pagets. Present study shows marked improvement with some apparent bony reconstruction and the left superior pubic ramus. There has certainly been no further bony destruction in the interior." On 4 September 1980 his physician gave him his last injection. In March 1986 he had a small basal cell carcinoma of the skin on his nose treated. He remained well until he died in August 1989 from a coronary.

Born in 1965, she was first seen in August 1981. In October 1979 she developed pain in her left shoulder. The deltoid muscle was enlarged and tender and overlaid a broad-based mass which involved the upper third of the humerus and was several centimeters thick. An x-ray showed the upper half of the humerus was abnormal. The lesion involved the entire cortex and medullary canal along with onion skinning. There was also a soft tissue mass in the deltoid region. She was diagnosed with Ewings sarcoma and given chemotherapy and radiotherapy for two years. In July 1981 residual tumor was still present. On 26 August 1981 I advised her to take ascorbic acid 12 g, niacinamide 3.0 g, pyridoxme 250 mg, zinc gluconate 100 mg, and dolomite 4 tablets, all daily.

In July 1984 she suffered a fracture of the humerus. Early in 1984 she had surgery to fill in the bone. In July 1985 she was well and was working. In 1989 she had a child. At 10-year follow-up she was well.

Born in 1957, he was first seen in June 1993. In 1981 he had a large liposarcoma removed from his leg. At first the surgeon thought the leg would have to be amputated. The mass was 10 by 5 cm large. After that he was given 30 irradiation sessions. He was well until three months before he saw me. By then he had another large mass in his abdomen which he could palpate. It was adherent to the peritoneum. The mass was removed and he was told he had a 25 percent chance it would not recur. He started himself on a good multivitamin program. I advised him to take ascorbic acid 12 g, B-complex SOs, niacinamide 1.5 g, beta carotene 50,000 iu, vitamin E 2,000 iu, selenium 300 mcg, zinc citrate 50 mg, and folic acid 15 mg, all daily. He was still well in September 1996. — Abram Hoffer

Patients with Cancer of the Uterus Surviving 8 or More Years

Born in 1943, she was first seen in February 1983. In 1972 she had an hysterectomy and oophorectomy for cancer of the uterus, followed by radiation. In 1981 carcinoma in situ on the labia was treated surgically. After I saw her she started to take ascorbic acid 2 g t.i.d., niacin 0.5 g t.i.d., 1-lysine for herpes 250 mg t.i.d., zinc sulfate 220 mg od, pyridoxine 250 mg od, and selenium 200 mcg od. She was not able to tolerate niacin and this was changed to niacinamide. By March 1984 she was free of genital herpes. In March 1988 she was normal and was still well in September 1996.

Born in 1946, she was first seen in August 1984. In May 1984, following a positive cone biopsy for cancer, she was advised to have an hysterectomy, but she refused. After I saw her she began to take ascorbic acid 4 g t.i.d., niacinamide 0.5 g t.i.d., vitamin E 400 iu od, and selenium 200 mcg od. Early in 1985 she did have her hysterectomy. She was alive and well in September 1996.

Born in 1914, she was first seen (for cancer) in August 1987. This patient first came to see me in 1985 for a variety of physical complaints, for which I started her on linodil (inositol niacinate) 3 grams per day and ascorbic acid 3 grams per day. In November 1986 she was infected with candida and was started on mycostatin. In July 1987 she noted that she was bleeding after voiding and on July 21 received a hysterectomy for cancer, diagnosed as Stage I endometrial adenocanthoma. I modified her program to include ascorbic acid 4 g t.i.d., linodil 2 g t.i.d., and vitamin KS mg od.

She reported 2 November 1987 that she had completed a series of radiation treatments. She was depressed at that time, and I therefore started her on Elavil 25 mg hs. In December 1987 her mood was good, she was no longer depressed. I added vitamin K 10 mg per day to her program and zinc chelate 30 mg per day. Her last cancer check up had been clear.

In June 1988 she reported she was on ascorbic acid 6 g per day, linodil 3 g per day, thyroid 60 mg od, mycostatin 1 million units t.i.d., folic acid 5 mg od, vitamin K 5 mg b.i.d., and selenium 200 mcg b.i.d. She was doing well. In June 1991 she was still doing very well and had had no recurrence of her cancer. She was still normal in September 1996. Patients with Ovarian Cancer Surviving 7 or More Years Out of 26 cases of ovarian cancer, 6 are alive for an average of 5.5 years, range 2 to 10. None of the controls survived the first year. Three patients lived over 7 years. Their brief histories are given below.

Born in 1941, she was first seen in May 1982. Early in 1981 both ovaries were removed. She was then started on chemotherapy, adriamyacin and cisplatinate, but treatment had to be stopped prematurely because her white cell count dropped too far. She had her last treatment in January. Following that she received radiation for six weeks. A laparotomy later that year showed there had been a recurrence. I advised her to take ascorbic acid 4 g t.i.d., niacinamide 0.5 g t.i.d., pyridoxine 250 mg od, zinc sulfate 220 mg od, selenium 200 micrograms od, and vitamin A 50,000 iu od. One month later she had reduced her ascorbic acid to 2 g daily, but by the end of the year she had been averaging 3 g od.

On 10 April 1984 she was found to have secondaries in her bones. She increased her ascorbic acid to 12 g o d and the selenium to 400 mcg. On 25 April 1985 she had further surgery, followed by 20 more radiations. By then she had a secondary carcinoma in the cerebellum causing severe headaches. On 7 April 1988 she was normal. She had remained on her vitamin regimen only until the end of November 1985. After ten years she was still well and follow-up was discontinued.

Born in 1918, she was first seen in Febmary 1989. In May 1985 both ovaries and the uterus were removed with cancer of the ovaries. After that she was given 3 sessions of chemotherapy and 32 sessions of radiation. Her attitude was positive. She watched her diet, exercised, and was active in a hope group. She was advised to start on calcium ascorbate 2 g t.i.d., niacinamide 0.5 g t.i.d., selenium 200 mcg b.i.d., beta carotene 10,000 iu per day, B-complex 50 mg od, and zinc citrate 50 mg od.

In September 1989 she was clear of cancer and still on her megavitamin program. In July 1991 she was still clear and was discharged from the cancer clinic. On 31 December 1991 she remained normal, free of any cancer, but she was developing a cataract in her eye. I added riboflavin 100 mg to her daily program. On November 1992 she was told by her ophthalmologist that there had been no further deterioration in her vision. She told me she was able to see better than before. Her mood was good. On 2 March 1993 she was still free of cancer, as she was on 3 September 1993 and 11 April 1994. Her only complaint was severe arthritis which had come on over the previous two months. She was still well in her seventies on September 1996.